Toxic phase
Although signs and symptoms may disappear for a day or two following the acute phase, 15 percent of those with acute yellow fever then enter a toxic phase. During the toxic phase, acute signs and symptoms return and more severe and life-threatening ones also appear. These can include:
Yellowing of your skin and the whites of your eyes (jaundice).
Abdominal pain and vomiting, sometimes bloodDecreased urination.
Bleeding from the nose, mouth and eyes.
Heart dysfunction (arrhythmias).
Liver and kidney failure.
Brain dysfunction including delirium, seizures and coma.
About 20 percent to 50 percent of those who enter the toxic phase die of the disease.
The rest usually recover without significant problems.
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